99%+ Purity • American Lab Tested • Free shipping $250+ • For Research Use Only Dismiss

GLP-R3

IN STOCK
IN STOCK

$ 200

Quantity

Product Discription

GLP-R3 (12mg)

Triple-Agonist Research Peptide – Multi-Receptor Metabolic Pathway Modeling & Energy-Signal Studies

GLP-R3 - Kaia Peptides GLP-R3 - Kaia Peptides

For laboratory research use only. Not for human or animal use. These products have not been evaluated by the U.S. Food and Drug Administration (FDA) and are not intended to diagnose, treat, cure, or prevent any disease.

What Is Retatrutide?

Retatrutide is a next-generation triple-agonist peptide used in advanced metabolic research.
It is studied for its ability to simultaneously activate:

  • GLP-1 receptors

  • GIP receptors

  • Glucagon receptors

This combination allows researchers to explore three interconnected metabolic pathways at once, providing a broader model for studying:

  • Appetite-related signaling

  • Energy-balance mechanisms

  • Glucose-regulation pathways

  • Lipid-metabolism models

  • Multi-receptor synergy in metabolic research

Because it engages three signaling systems instead of one, Retatrutide offers a highly versatile platform for examining complex metabolic behavior in controlled laboratory environments.


Understanding Retatrutide — A Metaphorical Research Analogy

Imagine a high-tech railway system used as a symbolic model of metabolic function.

This “train” represents an experimental metabolism system deciding:

  • How fuel (nutrients) moves

  • How signals regulate intake

  • How engines handle energy

  • How efficiently pathways communicate

  • How storage vs. utilization is balanced

In disrupted research models, the train may struggle with:

  • Faulty signals

  • Slow engines

  • Overloaded cargo

  • Inefficient fuel use

  • Reduced system responsiveness

Most metabolic-pathway agonists act like sending one engineer to help.

Retatrutide sends three.

Each specializes in a different signaling role.


Engineer #1 — The Signal Controller (GLP-1 Pathway Research)

The GLP-1–related component of Retatrutide is studied for:

  • Appetite-signaling pathways

  • Satiety-related neural circuits

  • Digestive-rate coordination

  • Hunger-cue modulation

In the railway analogy, this engineer repairs key signaling lights and switches so the system stops overloading with incoming fuel.


Engineer #2 — The Fuel Manager (GIP Pathway Research)

The GIP-related activity allows researchers to examine:

  • Insulin-signaling pathways

  • Fuel-utilization efficiency

  • Nutrient-processing behavior

  • Glucose-response mechanisms

In the metaphor, this engineer optimizes how fuel is handled after it arrives.


Engineer #3 — The Engine Modulator (Glucagon Pathway Research)

The glucagon-receptor component is used to study:

  • Energy-expenditure pathways

  • Lipid-mobilization models

  • Metabolic-activation signals

  • Fuel-burning mechanisms

This engineer goes directly to the engine room, adjusting power output and overall efficiency.


The Result: A Fully Coordinated Metabolic Railway (In Research Models)

With all three pathways engaged, researchers can explore:

  • Reduced signaling load in appetite models

  • Improved coordination of nutrient-handling systems

  • Enhanced mobilization of stored energy

  • Increased activation of metabolic pathways

  • Better synchronization across GLP-1, GIP, and glucagon networks

This railway analogy allows a clear visualization of triple-pathway receptor activation without implying any therapeutic or human outcome.


Combined Research Perspective

Retatrutide is valuable in studies involving:

  • Multi-hormone receptor interactions

  • Complex metabolic-pathway modeling

  • Fuel-handling and energy-output signals

  • Appetite-signaling cascades

  • Glucose-regulation frameworks

  • Lipid-metabolism dynamics

Scientists use this triple-agonist model to understand how overlapping receptors coordinate metabolic behavior in controlled environments.


For Research Use Only.
Not for human consumption. Not for medical, therapeutic, or veterinary use.
Descriptions are for scientific, laboratory, and educational reference only.

Explore

Discover Our Range of Peptide Solutions

IN STOCK
IN STOCK

BPC-157

$ 95

Add to cart
IN STOCK
IN STOCK

NAD+

$ 165

Add to cart
IN STOCK
IN STOCK

GLOW

$ 165

Add to cart
IN STOCK
IN STOCK

GLP-R3

$ 200

Add to cart
IN STOCK
IN STOCK

Semax

$ 100

Add to cart
IN STOCK
IN STOCK

MOTS-C

$ 95

Add to cart
IN STOCK
IN STOCK

PULSE

$ 125

Add to cart
OUT OF STOCK
OUT OF STOCK

ELEVATE

$ 175

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

WOLVERINE

$ 115

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

Tesamorelin

$ 135

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

Sermorelin

$ 100

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

KPV

$ 55

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

KLOW

$ 275

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

CJC-1295 (No DAC)

$ 85

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

AOD 9604

$ 75

Out of stock

Read more
OUT OF STOCK
OUT OF STOCK

SS-31

$ 145

Out of stock

Read more

FAQs

Find answers to your most pressing questions about peptide categories and their usage.

 
What is Retatrutide? +
Retatrutide is an experimental peptide studied as a triple agonist — interacting with GLP-1, GIP, and glucagon receptors in research models. Researchers often describe it as a “three-key molecule” that fits into three different metabolic locks.
Why is Retatrutide attracting scientific interest? +
Because it targets multiple metabolic pathways at once, Retatrutide is being studied for its impact on glucose regulation, energy expenditure, and appetite signaling in preclinical settings. Think of it as exploring how a single conductor can lead three different orchestras at the same time.
How does Retatrutide differ from peptides like Semaglutide? +
Semaglutide activates only GLP-1 receptors. Retatrutide engages GLP-1, GIP, AND glucagon receptors. It’s like comparing a single-gear bicycle (GLP-1 only) to a multi-gear system designed to shift across several terrains.
What do GLP-1, GIP, and glucagon pathways do? +
In research models: ● GLP-1 affects appetite signals and glucose regulation ● GIP is tied to insulin response and metabolic flexibility ● Glucagon influences energy expenditure and fat utilization Together, they act like three dials on the same metabolic control panel.
Why is Retatrutide sometimes called a “triple agonist”? +
Because it interacts with three receptors simultaneously, researchers use the term “triple agonist” to describe its mechanism. It’s similar to how a universal remote controls multiple devices at once.
What does research suggest about Retatrutide and metabolic efficiency? +
Animal studies show Retatrutide may influence body weight, energy expenditure, and glucose regulation. Scientists study it like examining how upgrading both the fuel system and the engine might change a car’s performance. (All findings refer strictly to preclinical research.)
Why is glucagon activation included? Doesn’t glucagon raise blood sugar? +
In isolation, glucagon elevates glucose — but in a multi-agonist framework, it may help increase metabolic output and fat utilization. Researchers examine how the combination behaves like balancing levers on a system rather than pulling just one lever alone.
How does Retatrutide compare to Tirzepatide (a dual agonist)? +
Tirzepatide stimulates GLP-1 and GIP. Retatrutide stimulates GLP-1, GIP, AND glucagon. Researchers compare the two like upgrading from a dual-engine aircraft to a tri-engine model — more complexity, more variables, more potential to study.
Is Retatrutide considered safe in research environments? +
Early animal data shows a favorable profile at studied doses, but Retatrutide is not FDA-approved, still experimental, and not intended for human use. Kaia provides it for research-only applications.
Why does Retatrutide often cause “potent” effects in studies? +
Because it targets multiple pathways at once, triple agonists can behave more forcefully in preclinical work — similar to how combining three amplifiers creates a louder, more noticeable signal than using one.
How should Retatrutide be stored for laboratory research? +
Retatrutide should be stored in a cool, dry, stable environment. Freezing is typically preferred for long-term stability. Peptides are like delicate microchips — the colder and darker the storage, the longer they retain integrity.
Is Retatrutide legal to purchase for research? +
Yes. Retatrutide is allowed for laboratory research use under U.S. standards, as long as it is not sold for human consumption, medical use, or veterinary use. Kaia complies fully with research-use-only labeling and distribution.